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It is notable that high spikes of blood insulin, (Hyperinsulinemia), initiates inflammation, which over times causes atherosclerosis and its sequela cardiovascular heart disease (CHD).ii High insulin is very, very bad

doi: 10.1096/fj.202001807 56 De PasqualeV.QuiccioneM

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Journal reference: Gasoyan, H., Schulte, R., Boyer, C

In addition, the lower mRNA expression levels of Bax and P53 and the higher expression levels of Bcl2 and Bcl-xL were detected in the peroxynitrite + ebselen group compared with the peroxynitrite-only group, while the lack of GPX1 in SGNs from gpx1 / mice led to an opposite pattern (Figure 8D)